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CD7 Mouse anti-Human, APC, Clone: 4H9, eBioscience™

Mouse Monoclonal Antibody

Brand:  Affymetrix eBioscience 17-0078-42

Code : NEW

Additional Details : Weight : 0.23750kg

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Product Code. 15537866

  • £152.25 / 100 tests


EU Stock 4
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Disclaimers:

For Research Use Only.


Description

Description

This 4H9 monoclonal antibody reacts with human CD7 (also known as Leu-9 or gp40), a 40kDa transmembrane glycoprotein belonging to the immunoglobulin superfamily. This molecule is expressed on peripheral blood T lymphocytes and natural killer cells, as well as on lymphoid and myeloid lineage precursors during adult hematopoiesis. Capable of providing a costimulatory signal and associating with CD3 and CD45, CD7 is involved in T cell activation.

CD7 has also been detected on numerous T cell-derived leukemias and lymphomias. In fact, because CD7 expression is greater on CD4+ T cells in classical Hodgkin’s lymphoma than in benign reactive lymph adenopathy, this molecule may be used as a diagnostic for Hodgkin’s lymphoma.

Blocking assays demonstrate that this clone recognizes the same epitope as clone 124-1D1.
Specifications

Specifications

CD7
4H9
APC
Conjugated
Murine
100 Tests
Store at 2-8°C. Do not freeze. Light-sensitive material.
Monoclonal
Flow Cytometry
5μL (0.25μg)/test
aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Leu-9
IgG2a
RUO
Primary
Human