CD7 Mouse anti-Human, APC, Clone: 4H9, eBioscience™

Mouse Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 17-0078-42

Code: NEW

Additional Details:
Additional Details: Weight: 0.23750kg



Disclaimers: For Research Use Only.

Product Code. 15537866

Quantity Price
1 £ 152.25 / 100 tests
EU Stock 8
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Description and Specification

Specification

Conjugate Allophycocyanin
Host Species Murine
Quantity 100 Tests
Primary or Secondary Primary
Antigen CD7
Isotype IgG2a
Regulatory Status RUO
Applications Flow Cytometry
Clone 4H9
Concentration 5μL (0.25μg)/test
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material.
Monoclonal or Polyclonal Monoclonal
Format Conjugated
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Gene Alias Leu-9
Species Reactivity Human

This 4H9 monoclonal antibody reacts with human CD7 (also known as Leu-9 or gp40), a 40kDa transmembrane glycoprotein belonging to the immunoglobulin superfamily. This molecule is expressed on peripheral blood T lymphocytes and natural killer cells, as well as on lymphoid and myeloid lineage precursors during adult hematopoiesis. Capable of providing a costimulatory signal and associating with CD3 and CD45, CD7 is involved in T cell activation.

CD7 has also been detected on numerous T cell-derived leukemias and lymphomias. In fact, because CD7 expression is greater on CD4+ T cells in classical Hodgkin’s lymphoma than in benign reactive lymph adenopathy, this molecule may be used as a diagnostic for Hodgkin’s lymphoma.

Blocking assays demonstrate that this clone recognizes the same epitope as clone 124-1D1.