CD7 Mouse anti-Human, APC, Clone: 4H9, eBioscience™
Mouse Monoclonal Antibody
Brand: Affymetrix eBioscience 17-0078-42
Code : NEW
Additional Details : Weight : 0.23750kg
DescriptionThis 4H9 monoclonal antibody reacts with human CD7 (also known as Leu-9 or gp40), a 40kDa transmembrane glycoprotein belonging to the immunoglobulin superfamily. This molecule is expressed on peripheral blood T lymphocytes and natural killer cells, as well as on lymphoid and myeloid lineage precursors during adult hematopoiesis. Capable of providing a costimulatory signal and associating with CD3 and CD45, CD7 is involved in T cell activation.
CD7 has also been detected on numerous T cell-derived leukemias and lymphomias. In fact, because CD7 expression is greater on CD4+ T cells in classical Hodgkin’s lymphoma than in benign reactive lymph adenopathy, this molecule may be used as a diagnostic for Hodgkin’s lymphoma.
Blocking assays demonstrate that this clone recognizes the same epitope as clone 124-1D1.
|aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer|
|Store at 2-8°C. Do not freeze. Light-sensitive material.|