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CD68 Mouse anti-Human, eFluor 570, Clone: 815CU17, eBioscience™

Mouse Monoclonal Antibody

Brand:  Affymetrix eBioscience 41-0687-80

Code : NEW

Additional Details : Weight : 0.09500kg

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Product Code. 15518926

  • £55.59 / 25µg


Estimated Shipment date
from Supplier 24-10-2017
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Disclaimers:

For Research Use Only.


Description

Description

This 815CU17 monoclonal antibody reacts with human CD68, a 110 kDa, transmembrane glycoprotein that belongs to the sialomucin family and is closely related to the lysosomal-associated membrane proteins (LAMP) and scavenger receptor. CD68 is predominantly an intracellular protein, found mainly in the late endosomal compartment but can be detected in smaller amounts on the surface of mainly myeloid-derived cells: monocytes, macrophages, dendritic cells (and in some langerhans cells), neutrophils, basophils, mast cells, myeloid progenitor cells, and a subset of CD34+ hematopoietic bone marrow progenitor cells. The function has not been fully elucidated but based on homology and structure, CD68 may play a role in antigen processing or presentation and protection of the lysosomal membrane from hydrolytic enzymes. Reports have also shown expression in activated T cells, and about 40% of peripheral blood B lymphocytes and 50% of all B-ALL.

This 815CU17 antibody does not cross-react with mouse or rat CD68.

For flow cytometric analysis of human CD68, we recommend clone eBioY1/82A.
Specifications

Specifications

CD68
815CU17
eFluor 570
Conjugated
IgG1
RUO
Primary
Human
Microscopy
0.2mg/mL
aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Murine
25μg
Store at 2-8°C. Do not freeze. Light-sensitive material.
Monoclonal