CD66e (CEA) Mouse anti-Human, Clone: CB30, eBioscience™

Mouse Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 14-0669-80

UNSPSC: 12352200

Code: Z2

Additional Details:
Additional Details: Weight: 0.01000kg



Disclaimers: For Research Use Only.

Product Code. 15287047

Quantity Price
1 £ 60.53 / 25µg
Estimated Shipment date
from Supplier 05-05-2017
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Description and Specification

Specification

Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Gene Alias Carcinoembryonic Antigen, CEACAM5
Primary or Secondary Primary
Applications Flow Cytometry
Applications Immunohistochemistry
Applications Western Blotting
Regulatory Status RUO
Conjugate Unlabeled
Isotype IgG1
Host Species Mouse
Monoclonal or Polyclonal Monoclonal
Clone CB30
Species Reactivity Human
Quantity 25μg
Antigen CD66e (CEA)
Storage Requirements Store at 2-8°C.
Concentration 0.5mg/mL
Format Purified

The monoclonal antibody CB30 recognizes human CD66e, also known as CEA (carcinoembryonic antigen) and CEACAM5. As a member of the immunoglobulin superfamily, it is large GPI-linked glycosylated protein with a molecular weight about 200 kDa. It is expressed mainly on epithelial cells and on a variety of tumors of the gastrointestinal, respiratory and genitourinary tracts. CD66e has been shown to function in cell adhesion and migration via homophilic and heterophilic interactions with NCA (non-specific cross-reacting antigen also known as CEACAM6 and CD66c). Overexpression is correlated with tumor invasiveness and is therefore used as a clinical marker.