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CD66e (CEA), clone: CB30, eBioscience™

Mouse Monoclonal Antibody

Brand:  Affymetrix eBioscience 14-0669-82

Code : Z2

Additional Details : Weight : 0.01000kg

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Product Code. 15297047

  • £163.84 / 100µg


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Description

Description

Description: The monoclonal antibody CB30 recognizes human CD66e, also known as CEA (carcinoembryonic antigen) and CEACAM5. As a member of the immunoglobulin superfamily, it is large GPI-linked glycosylated protein with a molecular weight about 200 kDa. It is expressed mainly on epithelial cells and on a variety of tumors of the gastrointestinal, respiratory and genitourinary tracts. CD66e has been shown to function in cell adhesion and migration via homophilic and heterophilic interactions with NCA (non-specific cross-reacting antigen also known as CEACAM6 and CD66c). Overexpression is correlated with tumor invasiveness and is therefore used as a clinical marker.Applications Reported: This CB30 antibody has been reported for use in flow cytometric analysis, immunoblotting (WB), and immunohistochemical staining.Applications Tested: This CB30 antibody has been tested by immunohistochemistry and by western blot on cell lysates prepared from MCF7 cells. This antibody can be used at less than or equal to 1 μg/mL for immunoblotting and less than 10 μg/mL for IHC. It is recommended that this antibody be carefully titrated for optimal performance in the assay of interest.Purity: Greater than 90%, as determined by SDS-PAGE.Aggregation: Less than 10%, as determined by HPLC.Filtration: 0.2μm post-manufacturing filtered.
Specifications

Specifications

CD66e (CEA)
Monoclonal
0.5mg/mL
PBS with 0.09% sodium azide; pH 7.2
P06731
meconium antigen 100, Carcinoembryonic Antigen, CD66e
Murine
Affinity chromatography
RUO
Antibody
Monoclonal
Human
Western Blot
CB30
Unconjugated
CEACAM5
Purified
CEACAM5
IgG1, kappa
100μg
Store at 2-8°C.
Primary
1048
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