CD66c Mouse anti-Human, PE, Clone: KOR-SA3544, eBioscience™

Mouse Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 12-0667-41

Code: NEW

Additional Details:
Additional Details: Weight: 0.23750kg



Disclaimers: For Research Use Only.

Product Code. 15526816

Quantity Price
1 £ 66.65 / 25 tests
EU Stock 6
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Description and Specification

Specification

Quantity 25 Tests
Host Species Murine
Monoclonal or Polyclonal Monoclonal
Regulatory Status RUO
Primary or Secondary Primary
Isotype IgG1
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Gene Alias CEACAM6
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material.
Clone KOR-SA3544
Applications Flow Cytometry
Antigen CD66c
Format Conjugated
Concentration 5μL (0.125μg)/test
Species Reactivity Human
Conjugate PE

This KOR-SA3544 monoclonal antibody reacts with human CD66c (also known as CEACAM6), which is one of the splice variants of CD66. CD66c is expressed on endothelial and epithelial cells, as well as on neutrophils and monocytes. Myeloma and cancer cells, such as B-cell acute lymphoblastic lymphomas, also express CD66c. Moreover, expression of this receptor can be induced on T cells, B cells, and CD16-negative NK cells. Like the other CD66 splice variants, CD66c is involved in cell adhesion and growth, neutrophil activation, and signaling. Moreover, expression of CD66c in leukemic cells has been correlated with BCR/ABL1 rearrangement. Finally, studies have shown that the CD66 variants interact with each other homo- and heterotypically.