CD66a (CEACAM1) Mouse anti-Human, APC, Clone: CD66a-B1.1, eBioscience™

Mouse Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 17-0668-42

Code: NEW

Additional Details:
Additional Details: Weight: 0.23750kg



Disclaimers: For Research Use Only.

Product Code. 15537966

Quantity Price
1 £ 170.59 / 100 tests
EU Stock 1
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Description and Specification

Specification

Isotype IgG2a
Gene Alias CEACAM1, CEACAM3, CEACAM6, CEA
Applications Flow Cytometry
Species Reactivity Human
Monoclonal or Polyclonal Monoclonal
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Host Species Mouse
Clone CD66a-B1.1
Concentration 5μL (0.06μg)/test
Primary or Secondary Primary
Format Conjugated
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material.
Quantity 100 tests
Antigen CD66a (CEACAM1)
Conjugate APC
Regulatory Status RUO

The CD66a-B1.1 monoclonal antibody reacts with human CD66a, c, d, and e, which are also known as CEACAM1, CEACAM6, CEACAM3 and CEA, respectively. CD66 is expressed on endothelial and epithelial cells, as well as on neutrophils and monocytes. Myeloma and cancer cells also express CD66. Moreover, expression of this receptor can be induced on T cells, B cells, and CD16-negative NK cells. CD66 exists as multiple splice variants that differ in the length of their cytoplasmic domain, which contains an immunoreceptor tyrosine-based inhibitory motif (ITIM) that mediates the inhibitory functions of this cell surface protein on T and NK cells. CD66 is involved in cell adhesion and growth, neutrophil activation, and signaling. Finally, studies have shown that the CD66 variants interact with each other homo- and heterotypically.