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CD66a (CEACAM1) Mouse anti-Human, APC, Clone: CD66a-B1.1, eBioscience™

Mouse Monoclonal Antibody

Brand:  Affymetrix eBioscience 17-0668-41

Code : NEW

Additional Details : Weight : 0.23750kg

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Product Code. 15527966

  • £66.65 / 25 tests


Estimated Shipment date
from Supplier 31-07-2017
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Disclaimers:

For Research Use Only.


Specifications

Description

The CD66a-B1.1 monoclonal antibody reacts with human CD66a, c, d, and e, which are also known as CEACAM1, CEACAM6, CEACAM3 and CEA, respectively. CD66 is expressed on endothelial and epithelial cells, as well as on neutrophils and monocytes. Myeloma and cancer cells also express CD66. Moreover, expression of this receptor can be induced on T cells, B cells, and CD16-negative NK cells. CD66 exists as multiple splice variants that differ in the length of their cytoplasmic domain, which contains an immunoreceptor tyrosine-based inhibitory motif (ITIM) that mediates the inhibitory functions of this cell surface protein on T and NK cells. CD66 is involved in cell adhesion and growth, neutrophil activation, and signaling. Finally, studies have shown that the CD66 variants interact with each other homo- and heterotypically.
Description & Specifications

Specifications

CD66a (CEACAM1)
CD66a-B1.1
Allophycocyanin
aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Murine
25 Tests
Store at 2-8°C. Do not freeze. Light-sensitive material.
Monoclonal
Flow Cytometry
5μL (0.06μg)/test
Conjugated
CEACAM1, CEACAM3, CEACAM6, CEA
IgG2a
RUO
Primary
Human