CD66a (CEACAM1) Mouse anti-Human, APC, Clone: CD66a-B1.1, eBioscience™

Mouse Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 17-0668-41

Code: NEW

Additional Details:
Additional Details: Weight: 0.23750kg



Disclaimers: For Research Use Only.

Product Code. 15527966

Quantity Price
1 £ 66.65 / 25 tests
Estimated Shipment date
from Supplier 05-05-2017
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Description and Specification

Specification

Conjugate Allophycocyanin
Quantity 25 Tests
Host Species Murine
Gene Alias CEACAM1, CEACAM3, CEACAM6, CEA
Isotype IgG2a
Antigen CD66a (CEACAM1)
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material.
Monoclonal or Polyclonal Monoclonal
Clone CD66a-B1.1
Concentration 5μL (0.06μg)/test
Format Conjugated
Species Reactivity Human
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Primary or Secondary Primary
Regulatory Status RUO
Applications Flow Cytometry

The CD66a-B1.1 monoclonal antibody reacts with human CD66a, c, d, and e, which are also known as CEACAM1, CEACAM6, CEACAM3 and CEA, respectively. CD66 is expressed on endothelial and epithelial cells, as well as on neutrophils and monocytes. Myeloma and cancer cells also express CD66. Moreover, expression of this receptor can be induced on T cells, B cells, and CD16-negative NK cells. CD66 exists as multiple splice variants that differ in the length of their cytoplasmic domain, which contains an immunoreceptor tyrosine-based inhibitory motif (ITIM) that mediates the inhibitory functions of this cell surface protein on T and NK cells. CD66 is involved in cell adhesion and growth, neutrophil activation, and signaling. Finally, studies have shown that the CD66 variants interact with each other homo- and heterotypically.