CD65 Mouse anti-Human, FITC, Clone: VIM8, eBioscience™

Mouse Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 11-0659-42

Code: NEW

Additional Details:
Additional Details: Weight: 0.23750kg



Disclaimers: For Research Use Only.

Product Code. 15566436

Quantity Price
1 £ 182.82 / 100 tests
Estimated Shipment date
from Supplier 05-05-2017
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Description and Specification

Specification

Quantity 100 Tests
Host Species Murine
Applications Flow Cytometry
Conjugate FITC
Primary or Secondary Primary
Regulatory Status RUO
Clone VIM8
Monoclonal or Polyclonal Monoclonal
Antigen CD65
Isotype IgM
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material.
Species Reactivity Human
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Format Conjugated
Gene Alias Fucoganglioside Type II
Concentration 5μL (0.25μg)/test

This VIM8 antibody reacts with the desialylated asialoganglioside of human CD65. This type 2 fucosylated carbohydrate antigen is expressed on the surface of all myeloid cells during development. Moreover, CD65 is expressed highly on granulocytes and weakly on monocytes in peripheral blood. CD65 has been reported to be a ligand for CD62E (E-Selectin). However, the sialylated form of CD65 (designated CD65s) can be used as a marker for acute myeloid leukemia (AML) as its expression increases as CD34 decreases. Finally, CD65 is important for extravascular infiltration of AML cells.