CD63 Rat anti-Mouse, PE-Cy7, Clone: NVG-2, eBioscience™

Rat Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 25-0631-82

Code: NEW

Additional Details:
Additional Details: Weight: 0.09500kg



Disclaimers: For Research Use Only.

Product Code. 15598416

Quantity Price
1 £ 182.82 / 100µg
Estimated Shipment date
from Supplier 04-05-2017
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Description and Specification

Specification

Quantity 100μg
Isotype IgG2a
Primary or Secondary Primary
Species Reactivity Mouse
Format Conjugated
Concentration 0.2mg/mL
Applications Flow Cytometry (Intracellular Staining)
Monoclonal or Polyclonal Monoclonal
Gene Alias LAMP3, DC-LAMP, LIMP-1, TSPAN30, MLA1, ME491, granulophysin
Host Species Rat
Regulatory Status RUO
Antigen CD63
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material. This tandem dye is sensitive to photo-induced oxidation. Protect this vial from light during storage
Conjugate PE-Cy7
Clone NVG-2
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer

The monoclonal antibody NVG-2 reacts with mouse CD63, also known as Lysosomal-Associated Membrane Protein 3 (LAMP-3) or tetraspanin 30 (TSPN30), a member of tetraspanin family of proteins characterized by four transmembrane domains. CD63 is expressed on a variety of cell types of hematopoietic lineage, e.g., granulocytes, B lymphocytes, platelets, as well as cells of non-hematopoietic origin. It can be found on the cell membrane, late endocytic vesicles, lysosomes, exosomes, and other specialized granules. On the cell surface, CD63 has been shown to interact with various proteins forming tetraspanin-enriched microdomains (TEM). Its high expression on the cell membrane may be indicative of cell activation, hence, CD63 is often used as an activation marker for basophils, platelets and other cells.