CD63 Rat anti-Mouse, PE-Cy7, Clone: NVG-2, eBioscience™

Rat Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 25-0631-80

Code: NEW

Additional Details:
Additional Details: Weight: 0.09500kg



Disclaimers: For Research Use Only.

Product Code. 15588416

Quantity Price
1 £ 84.99 / 25µg
Estimated Shipment date
from Supplier 08-05-2017
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Description and Specification

Specification

Gene Alias LAMP3, DC-LAMP, LIMP-1, TSPAN30, MLA1, ME491, granulophysin
Regulatory Status RUO
Species Reactivity Mouse
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material. This tandem dye is sensitive to photo-induced oxidation. Protect this vial from light during storage
Format Conjugated
Clone NVG-2
Isotype IgG2a
Antigen CD63
Conjugate PE-Cy7
Applications Flow Cytometry (Intracellular Staining)
Concentration 0.2mg/mL
Primary or Secondary Primary
Monoclonal or Polyclonal Monoclonal
Quantity 25μg
Host Species Rat
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer

The monoclonal antibody NVG-2 reacts with mouse CD63, also known as Lysosomal-Associated Membrane Protein 3 (LAMP-3) or tetraspanin 30 (TSPN30), a member of tetraspanin family of proteins characterized by four transmembrane domains. CD63 is expressed on a variety of cell types of hematopoietic lineage, e.g., granulocytes, B lymphocytes, platelets, as well as cells of non-hematopoietic origin. It can be found on the cell membrane, late endocytic vesicles, lysosomes, exosomes, and other specialized granules. On the cell surface, CD63 has been shown to interact with various proteins forming tetraspanin-enriched microdomains (TEM). Its high expression on the cell membrane may be indicative of cell activation, hence, CD63 is often used as an activation marker for basophils, platelets and other cells.