CD63 Mouse anti-Human, eFluor 660, Clone: H5C6, eBioscience™

Mouse Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 50-0639-41

Code: NEW

Additional Details:
Additional Details: Weight: 0.23750kg



Disclaimers: For Research Use Only.

Product Code. 15549886

Quantity Price
1 £ 68.45 / 25 tests
EU Stock 1
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Description and Specification

Specification

Isotype IgG1
Format Conjugated
Monoclonal or Polyclonal Monoclonal
Host Species Mouse
Applications Flow Cytometry
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material.
Quantity 25 tests
Clone H5C6
Conjugate eFluor 660
Regulatory Status RUO
Primary or Secondary Primary
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Antigen CD63
Species Reactivity Human
Gene Alias Lysosome-associated membrane protein 3, Lamp 3
Concentration 5μL (0.5μg)/test

This H5C6 monoclonal antibody reacts with human CD63, a type III member of the tetraspanin family of transmembrane proteins. CD63 is expressed intracellularly on lysosomes, endosomes, and granules of resting platelets and basophils. However, cell surface expression of CD63 can be detected on activated basophils and platelets, monocytes, macrophages, and granulocytes. This receptor is also expressed on endothelial cells, fibroblasts, and smooth muscle cells. Studies have demonstrated that CD63 associates with integrins (VLA-3 and VLA-6) and TIMP-1 to mediate the allergic response.