CD63 Mouse anti-Human, eFluor 450, Clone: H5C6, eBioscience™

Mouse Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 48-0639-41

Code: NEW

Additional Details:
Additional Details: Weight: 0.23750kg



Disclaimers: For Research Use Only.

Product Code. 15589686

Quantity Price
1 £ 80.62 / 25 tests
Estimated Shipment date
from Supplier 03-05-2017
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Description and Specification

Specification

Regulatory Status RUO
Isotype IgG1
Conjugate eFluor 450
Monoclonal or Polyclonal Monoclonal
Antigen CD63
Gene Alias Lysosome-associated membrane protein 3, Lamp 3
Species Reactivity Human
Format Conjugated
Primary or Secondary Primary
Concentration 5μL (1.0μg)/test
Quantity 25 tests
Host Species Mouse
Clone H5C6
Applications Flow Cytometry
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material.

This H5C6 monoclonal antibody reacts with human CD63, a type III member of the tetraspanin family of transmembrane proteins. CD63 is expressed intracellularly on lysosomes, endosomes, and granules of resting platelets and basophils. However, cell surface expression of CD63 can be detected on activated basophils and platelets, monocytes, macrophages, and granulocytes. This receptor is also expressed on endothelial cells, fibroblasts, and smooth muscle cells. Studies have demonstrated that CD63 associates with integrins (VLA-3 and VLA-6) and TIMP-1 to mediate the allergic response.