CD63 Mouse anti-Human, eFluor 450, Clone: H5C6, eBioscience™

Mouse Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 48-0639-42

Code: NEW

Additional Details:
Additional Details: Weight: 0.23750kg



Disclaimers: For Research Use Only.

Product Code. 15599686

Quantity Price
1 £ 198.54 / 100 tests
Estimated Shipment date
from Supplier 04-05-2017
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Description and Specification

Specification

Monoclonal or Polyclonal Monoclonal
Applications Flow Cytometry
Quantity 100 tests
Isotype IgG1
Concentration 5μL (1.0μg)/test
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material.
Antigen CD63
Regulatory Status RUO
Format Conjugated
Primary or Secondary Primary
Host Species Mouse
Conjugate eFluor 450
Gene Alias Lysosome-associated membrane protein 3, Lamp 3
Clone H5C6
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Species Reactivity Human

This H5C6 monoclonal antibody reacts with human CD63, a type III member of the tetraspanin family of transmembrane proteins. CD63 is expressed intracellularly on lysosomes, endosomes, and granules of resting platelets and basophils. However, cell surface expression of CD63 can be detected on activated basophils and platelets, monocytes, macrophages, and granulocytes. This receptor is also expressed on endothelial cells, fibroblasts, and smooth muscle cells. Studies have demonstrated that CD63 associates with integrins (VLA-3 and VLA-6) and TIMP-1 to mediate the allergic response.