CD62P (P-Selectin), APC, clone: Psel.KO2.3, eBioscience™
Mouse Monoclonal Antibody
Brand: Affymetrix eBioscience 17-0626-80
Code : Z2
Additional Details : Weight : 0.25000kg
DescriptionDescription: The Psel.KO2.3 monoclonal antibody reacts with mouse CD62P (also known as P-selectin and GMP-140), a 140-kDa cell adhesion molecule that can be induced on endothelial cells and platelets. During inflammation, this selectin mediates adhesion of monocytes and neutrophils to activated platelets, as well as leukocyte rolling on endothelial cells. The major ligand for CD62P on neutrophils is P-selectin glycoprotein ligand-1 (PSGL-1). This monoclonal antibody recognizes an epitope that is conserved across several species (e.g. mouse, human, and rat) and has not been reported to block cell adhesion.Applications Reported: This Psel.KO2.3 antibody has been reported for use in flow cytometric analysis.Applications Tested: This Psel.KO2.3 antibody has been tested by flow cytometric analysis on thrombin-activated human platelets. This can be used at less than or equal to 0.25 μg per test. A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest.Excitation: 633-647 nm; Emission: 660 nm; Laser: Red Laser.Filtration: 0.2μm post-manufacturing filtered.
|PBS with 0.1% gelatin and 0.09% sodium azide; pH 7.2|
|RP1-86F14.2, CD62, CD62P, FLJ45155, GMP140, GRMP, LECAM3, PADGEM, PSEL|
|Store at 2-8°C. Do not freeze. Light-sensitive material.|
For Research Use Only.