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CD62P (P-Selectin), clone: AK-4, eBioscience™

Mouse Monoclonal Antibody

Brand:  Affymetrix eBioscience 14-0628-80

Code : Z2

Additional Details : Weight : 0.01000kg

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Product Code. 15217047

  • £31.05 / 25µg


Estimated Shipment
06-07-2018
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Description

Description

Description: The AK-4 monoclonal antibody reacts with human CD62P, a 140kDa transmembrane glycoprotein also known as P-Selectin. Upon activation, CD62P is rapidly transported from its cytoplasmic stores in the Weibel-Palade bodies of endothelial cells or the alpha-granules of platelets to the surface. CD62P initiates the adhesive interaction between endothelial cells and neutrophils and monocytes during the inflammatory reaction and is also involved in the interaction of platelets with monocytes and neutrophils.Applications Reported: The AK-4 antibody has been reported for use in flow cytometric analysis, and immunohistochemical staining of frozen tissue sections. AK-4 has also been reported in blocking adhesion of platelets in in vitro assays. (Please use Functional Grade purified AK-4, cat. 16-0628, in functional assays.).Applications Tested: This AK-4 antibody has been tested by flow cytometric analysis of resting and thrombin-activated human platelets. This can be used at less than or equal to 1 μg per test. A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest.Purity: Greater than 90%, as determined by SDS-PAGE.Aggregation: Less than 10%, as determined by HPLC.Filtration: 0.2μm post-manufacturing filtered.
Specifications

Specifications

CD62P (P-Selectin)
Monoclonal
0.5mg/mL
PBS with 0.09% sodium azide; pH 7.2
P16109
RP1-86F14.2, CD62, CD62P, FLJ45155, GMP140, GRMP, LECAM3, PADGEM, PSEL
Murine
Affinity chromatography
RUO
Antibody
Monoclonal
Human
Flow CytometryþFunctional AssayþImmunohistochemistry (Frozen)
AK-4
Unconjugated
SELP
Purified
SELP
IgG1, kappa
25μg
Store at 2-8°C.
Primary
6403
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