CD62E (E-Selectin) Mouse anti-Human, Clone: P2H3, eBioscience™

Mouse Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 14-0627-80

25UG:ANTI-HUMAN CD62E (E-SELECTIN) PURIFIED 25 UG

UNSPSC: 12352200

Code: Z2

Additional Details:
Additional Details: Weight: 0.01000kg



Disclaimers: For Research Use Only.

Product Code. 15297037

Quantity Price
1 £ 70.0 / 25µg
Estimated Shipment date
from Supplier 08-12-2016
Add to basket


Description and Specification

Specification

Antigen CD62E (E-Selectin)
Applications Flow Cytometry
Applications Functional Assay
Applications Immunohistochemistry
Applications Immunoprecipitation
Clone P2H3
Concentration 0.5mg/mL
Conjugate Unlabeled
Format Purified
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Gene Alias LECAM-2
Host Species Mouse
Isotype IgG1
Quantity 25μg
Regulatory Status RUO
Species Reactivity Human
Storage Requirements Store at 2-8°C.
Primary or Secondary Primary
Monoclonal or Polyclonal Monoclonal

The P2H3 monoclonal antibody reacts with human CD62E, a 97-115kDa member of the selectin family. CD62E, also known as E-selectin or endothelial-leukocyte adhesion molecule-1 (ELAM-1) is an adhesion molecule expressed by endothelial cells upon stimulation with cytokines including TNFα and IL-1β. Induced expression of CD62E during inflammatory conditions is thought to mediate leukocyte rolling including the initial interaction of neutrophils with endothelium.

The P2H3 monoclonal antibody also inhibits cellular adhesion to cytokine-activated endothelial cells.