CD62E (E-Selectin) Mouse anti-Human, Clone: P2H3, eBioscience™

Mouse Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 14-0627-80

UNSPSC: 12352200

Code: Z2

Additional Details:
Additional Details: Weight: 0.01000kg



Disclaimers: For Research Use Only.

Product Code. 15297037

Quantity Price
1 £ 42.19 / 25µg
Estimated Shipment date
from Supplier 09-05-2017
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Description and Specification

Specification

Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Applications Flow Cytometry
Applications Functional Assay
Applications Immunohistochemistry
Applications Immunoprecipitation
Species Reactivity Human
Clone P2H3
Concentration 0.5mg/mL
Gene Alias LECAM-2
Regulatory Status RUO
Antigen CD62E (E-Selectin)
Quantity 25μg
Host Species Mouse
Primary or Secondary Primary
Isotype IgG1
Storage Requirements Store at 2-8°C.
Monoclonal or Polyclonal Monoclonal
Format Purified
Conjugate Unlabeled

The P2H3 monoclonal antibody reacts with human CD62E, a 97-115kDa member of the selectin family. CD62E, also known as E-selectin or endothelial-leukocyte adhesion molecule-1 (ELAM-1) is an adhesion molecule expressed by endothelial cells upon stimulation with cytokines including TNFα and IL-1β. Induced expression of CD62E during inflammatory conditions is thought to mediate leukocyte rolling including the initial interaction of neutrophils with endothelium.

The P2H3 monoclonal antibody also inhibits cellular adhesion to cytokine-activated endothelial cells.