CD62E (E-Selectin) Mouse anti-Human, Clone: P2H3, eBioscience™

Mouse Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 14-0627-82

UNSPSC: 12352200

Code: Z2

Additional Details:
Additional Details: Weight: 0.01000kg



Disclaimers: For Research Use Only.

Product Code. 15207047

Quantity Price
1 £ 72.77 / 100µg
Estimated Shipment date
from Supplier 03-04-2017
Add to basket


Description and Specification

Specification

Applications Flow Cytometry
Applications Functional Assay
Applications Immunohistochemistry
Applications Immunoprecipitation
Host Species Mouse
Isotype IgG1
Concentration 0.5mg/mL
Storage Requirements Store at 2-8°C.
Antigen CD62E (E-Selectin)
Species Reactivity Human
Conjugate Unlabeled
Primary or Secondary Primary
Monoclonal or Polyclonal Monoclonal
Gene Alias LECAM-2
Regulatory Status RUO
Quantity 100μg
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Clone P2H3
Format Purified

The P2H3 monoclonal antibody reacts with human CD62E, a 97-115kDa member of the selectin family. CD62E, also known as E-selectin or endothelial-leukocyte adhesion molecule-1 (ELAM-1) is an adhesion molecule expressed by endothelial cells upon stimulation with cytokines including TNFα and IL-1β. Induced expression of CD62E during inflammatory conditions is thought to mediate leukocyte rolling including the initial interaction of neutrophils with endothelium.

The P2H3 monoclonal antibody also inhibits cellular adhesion to cytokine-activated endothelial cells.