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CD59 (Protectin) Mouse anti-Human, APC, Clone: OV9A2, eBioscience™

Mouse Monoclonal Antibody

Brand:  Affymetrix eBioscience 17-0596-42

Code : NEW

Additional Details : Weight : 0.23750kg

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Product Code. 15537956

  • £133.91 / 100 tests


EU Stock 10
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Disclaimers:

For Research Use Only.


Description

Description

This OV9A2 monoclonal antibody reacts with human CD59, which is also known as Protectin. This GPI-linked membrane glycoprotein shares structural homology with the murine Ly-6 superfamily. CD59 is expressed on all human lymphocytes, monocytes, granulocytes, and erythrocytes. This protein is also expressed on non-hematopoietic cells, including endothelial cells and neurons. By binding the complement components C8 and C9, CD59 inhibits assembly of the membrane attack complex and cytolytic activity by complement. CD59 interacts with CD2 to modulate T cell adhesion, and also plays a role in T cell activation. Finally, altered expression of CD55 and CD59 on human peripheral blood cells has been observed in patients with systemic lupus erythematosus (SLE).

Crossblocking studies indicate that the OV9A2 monoclonal antibody binds the same epitope as MEM-43.
Specifications

Specifications

CD59/Protectin
OV9A2
APC
Conjugated
Murine
100 Tests
Store at 2-8°C. Do not freeze. Light-sensitive material.
Monoclonal
Flow Cytometry
5μL (0.125μg)/test
aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
MIRL
IgG1
RUO
Primary
Human