missing translation for 'onlineSavingsMsg'
Learn More

CD58 (LFA-3), APC, clone: TS2/9, eBioscience™

Mouse Monoclonal Antibody

Brand:  Affymetrix eBioscience 17-0578-42

Code : NEW

Additional Details : Weight : 0.23750kg

 View more versions of this product

Product Code. 15517956

  • £158.98 / 100 tests


Estimated Shipment date
from Supplier 02-07-2018
Add to basket

Description

Description

Description: The TS2/9 antibody recognizes human CD58, which is also known as Lymphocyte Associated Antigen-3 (LFA-3). CD58 exists both as a transmembrane protein as well as a GPI-linked extracellular protein. It has been shown that cells can express both forms concurrently. In addition, soluble CD58 has also been observed in serum, urine and synoval fluid of rheumatoid arthritis patients. CD58 is found on non-hematopoietic and most hematopoietic cells. Binding to its ligand CD2, which is present on T cells, initiates a signaling pathway which includes phosphorylation and results in release of cytokines. CD58 has been shown to be important in adhesion to various cell types, T cell activation, cytokine production and cytoxicity. The TS2/9 antibody has been reported to induce signaling events upon crosslinking. The epitope is in domain 1 of the immunoglobulin region.Applications Reported: This TS2/9 antibody has been reported for use in flow cytometric analysis.Applications Tested: This TS2/9 antibody has been pre-titrated and tested by flow cytometric analysis of normal peripheral blood cells. This can be used at 5 μL (0.5 μg) per test. A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test.Excitation: 633-647 nm; Emission: 660 nm; Laser: Red Laser.Filtration: 0.2μm post-manufacturing filtered.
Specifications

Specifications

CD58
Monoclonal
5μl/Test
PBS with 0.1% gelatin, 0.2% BSA and 0.09% sodium azide; pH 7.2
P19256
LFA-3, LFA3
Murine
Affinity chromatography
RUO
Antibody
Monoclonal
Human
Flow Cytometry
TS2/9
APC
CD58
Conjugated
CD58
IgG1
100 Tests
Store at 2-8°C. Do not freeze. Light-sensitive material.
Primary
965
Videos

For Research Use Only.