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CD54 (ICAM-1) Rat anti-Mouse, PE, Clone: KAT-1, eBioscience™

Rat Monoclonal Antibody

Brand:  Affymetrix eBioscience 12-0542-82

Code : Z2

Additional Details : Weight : 0.25000kg

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Product Code. 15258569

  • £115.56 / 100µg


EU Stock 1
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Disclaimers:

For Research Use Only.


Description

Description

The eBioKAT-1 monoclonal antibody reacts with mouse CD54 (ICAM-1), which is a 95kDa member of the immunoglobulin superfamily. CD54 is expressed at low levels on leukocytes and high endothelial venules, and expression increases in response to inflammatory cytokines. ICAM-1 binds to LFA-1 and this interaction is required for the transendothelial migration of T cells. ICAM-1-deficient mice are viable, however the migration of leukocytes to sites of inflammation is reduced leading to impaired immune and inflammatory responses. Based on the regulated expression of ICAM-1, it has been suggested that ICAM-1 may increase leukocyte extravasation at sites of inflammation, whereas the constitutively high expression of ICAM-2 mediates leukocyte traffic into non-inflamed tissue. The eBioKAT-1 monoclonal antibody recognizes a different epitope than the YN1/1.7.4 monoclonal antibody.
Specifications

Specifications

CD54 (ICAM-1)
KAT1)
PE
Conjugated
Rat
100μg
Store at 2-8°C. Do not freeze. Light-sensitive material.
Monoclonal
Flow Cytometry
0.2mg/mL
aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Intercellular adhesion molecule-1
IgG2a
RUO
Primary
Murine
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