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CD51/CD61 (Integrin alpha v beta 3), FITC, clone: 23C6, eBioscience™

Mouse Monoclonal Antibody

Brand:  Affymetrix eBioscience 11-0519-41

Code : NEW

Additional Details : Weight : 0.23750kg

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Product Code. 15566416

  • £49.53 / 25 tests


Estimated Shipment date
from Supplier 21-02-2018
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Disclaimers:

For Research Use Only.


Description

Description

Description: The 23C6 monoclonal antibody reacts with the human CD51/CD61 dimer, also known as the integrin alphav/beta3. CD51, an ∽120kDa surface molecule can also non-covalently associate with other beta subunits of the integrin family including beta1 (CD29), beta5 and beta6 to form receptors for extracellular matrix components. Heterodimers of CD51/CD61 are expressed by melanoma cells, endothelial cells and osteoclasts and at very low levels by platelets. The CD51/CD61 complex mediates adhesion to fibrinogen, fibronectin, vitronectin and thrombospondin.Applications Reported: The 23C6 antibody has been reported for use in flow cytometric analysis.Applications Tested: The 23C6 antibody has been pre-titrated and tested by flow cytometric analysis of human melanoma cell line and peripheral blood cells. This can be used at 5 μL (1 μg) per test. A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test.Excitation: 488 nm; Emission: 520 nm; Laser: Blue Laser.Filtration: 0.2μm post-manufacturing filtered.
Specifications

Specifications

CD51/CD61
23C6
FITC
Conjugated
Murine
25 Tests
Store at 2-8°C. Do not freeze. Light-sensitive material.
Monoclonal
Flow Cytometry
5μL (1μg)/test
aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Integrin av b3, vitronectin Receptor
IgG1
RUO
Primary
Human
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