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CD51/CD61 (Integrin alpha v beta 3), FITC, clone: 23C6, eBioscience™

Mouse Monoclonal Antibody

Brand:  Affymetrix eBioscience 11-0519-41

Code : NEW

Additional Details : Weight : 0.23750kg

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Product Code. 15566416

  • £49.53 / 25 tests


Estimated Shipment date
from Supplier 03-07-2018
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Description

Description

Description: The 23C6 monoclonal antibody reacts with the human CD51/CD61 dimer, also known as the integrin alphav/beta3. CD51, an ∽120kDa surface molecule can also non-covalently associate with other beta subunits of the integrin family including beta1 (CD29), beta5 and beta6 to form receptors for extracellular matrix components. Heterodimers of CD51/CD61 are expressed by melanoma cells, endothelial cells and osteoclasts and at very low levels by platelets. The CD51/CD61 complex mediates adhesion to fibrinogen, fibronectin, vitronectin and thrombospondin.Applications Reported: The 23C6 antibody has been reported for use in flow cytometric analysis.Applications Tested: The 23C6 antibody has been pre-titrated and tested by flow cytometric analysis of human melanoma cell line and peripheral blood cells. This can be used at 5 μL (1 μg) per test. A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test.Excitation: 488 nm; Emission: 520 nm; Laser: Blue Laser.Filtration: 0.2μm post-manufacturing filtered.
Specifications

Specifications

CD51/CD61
Monoclonal
5μl/Test
PBS with 0.1% gelatin, 0.2% BSA and 0.09% sodium azide; pH 7.2
P05106, P06756
ITGAV, ITGB3, CD51, MSK8, VNRA, VTNR, integrin alpha-V, integrin alphaVbeta3, antigen CD51, vitronectin receptor subunit alpha, CD61, GP3A, GPIIIa
Murine
Affinity chromatography
RUO
Antibody
Monoclonal
Human
Flow Cytometry
23C6
FITC
ITGAV
Conjugated
ITGAV, ITGB3
IgG1, kappa
25 Tests
Store at 2-8°C. Do not freeze. Light-sensitive material.
Primary
3685, 3690
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