CD51/CD61 (Integrin alpha v beta 3) Mouse anti-Human, FITC, Clone: 23C6, eBioscience™

Mouse Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 11-0519-41

Code: NEW

Additional Details:
Additional Details: Weight: 0.23750kg



Disclaimers: For Research Use Only.

Product Code. 15566416

Quantity Price
1 £ 48.31 / 25 tests
Estimated Shipment date
from Supplier 28-04-2017
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Description and Specification

Specification

Format Conjugated
Conjugate FITC
Isotype IgG1
Host Species Mouse
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material.
Gene Alias Integrin av b3, vitronectin Receptor
Concentration 5μL (1μg)/test
Clone 23C6
Primary or Secondary Primary
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Species Reactivity Human
Antigen CD51/CD61 (Integrin alpha v beta 3)
Quantity 25 tests
Regulatory Status RUO
Applications Flow Cytometry
Monoclonal or Polyclonal Monoclonal

The 23C6 monoclonal antibody reacts with the human CD51/CD61 dimer, also known as the integrin αv/β3. CD51, an ∽120kDa surface molecule can also non-covalently associate with other β subunits of the integrin family including β1 (CD29), β5 and β6 to form receptors for extracellular matrix components. Heterodimers of CD51/CD61 are expressed by melanoma cells, endothelial cells and osteoclasts and at very low levels by platelets. The CD51/CD61 complex mediates adhesion to fibrinogen, fibronectin, vitronectin and thrombospondin.