missing translation for 'onlineSavingsMsg'
Learn More

CD51/CD61 (Integrin alpha v beta 3) Mouse anti-Human, FITC, Clone: 23C6, eBioscience™

Mouse Monoclonal Antibody

£53.75 - £123.00

Specifications

Antigen CD51/CD61 (Integrin alpha v beta 3)
Clone 23C6
Target Species Human
Conjugate FITC
Isotype IgG1, kappa
View More Specs

Products 2
Product Code Brand Quantity Price Quantity & Availability  
Product Code Brand Quantity Price Quantity & Availability  
15566416
View Documents
Affymetrix eBioscience
11-0519-41
25 Tests
£53.75
25 tests
View alternative products
Save Up to 
»
Estimated Shipment
03-03-2021
Please to purchase this item. Need a web account? Register with us today!
15576416
View Documents
Affymetrix eBioscience
11-0519-42
100 Tests
£123.00
100 tests
View alternative products
Save Up to 
»
In stock, ready to ship: 1 Please to purchase this item. Need a web account? Register with us today!
Description

Description

Description: The 23C6 monoclonal antibody reacts with the human CD51/CD61 dimer, also known as the integrin alphav/beta3. CD51, an ∽120 kDa surface molecule can also non-covalently associate with other beta subunits of the integrin family including beta1 (CD29), beta5 and beta6 to form receptors for extracellular matrix components. Heterodimers of CD51/CD61 are expressed by melanoma cells, endothelial cells and osteoclasts and at very low levels by platelets. The CD51/CD61 complex mediates adhesion to fibrinogen, fibronectin, vitronectin and thrombospondin. Applications Reported: The 23C6 antibody has been reported for use in flow cytometric analysis. Applications Tested: The 23C6 antibody has been pre-titrated and tested by flow cytometric analysis of human melanoma cell line and peripheral blood cells. This can be used at 5 µL (1 µg) per test. A test is defined as the amount (µg) of antibody that will stain a cell sample in a final volume of 100 µL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. Excitation: 488 nm; Emission: 520 nm; Laser: Blue Laser. Filtration: 0.2 μm post-manufacturing filtered.

MA1-33578 recognized the intact complex formed between the CD51 and CD61 molecules (alpha V and beta 3 integrins). This complex binds vitronection at the RGD sequence and can also bind fibrinogen, von Willebrand factor, thrombospondin, fibronectin, osteopontin and collagen. Reacts with osteoclasts, placenta, melanoma cell lines and weakly with platelets.
Specifications

Specifications

CD51/CD61 (Integrin alpha v beta 3)
Human
IgG1, kappa
Monoclonal
Liquid
Antibody
4° C, store in dark, DO NOT FREEZE!
23C6
FITC
Flow Cytometry
Primary
Monoclonal
PBS with 0.1% gelatin, 0.2% BSA and 0.09% sodium azide; pH 7.2
RUO
SDS

For Research Use Only.