CD51/CD61 (Integrin alpha v beta 3) Mouse anti-Human, Clone: 23C6, eBioscience™

Mouse Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 14-0519-82

UNSPSC: 12352200

Code: Z2

Additional Details:
Additional Details: Weight: 0.01000kg



Disclaimers: For Research Use Only.

Product Code. 15267017

Quantity Price
1 £ 60.53 / 100µg
Estimated Shipment date
from Supplier 03-05-2017
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Description and Specification

Specification

Quantity 100μg
Regulatory Status RUO
Isotype IgG1
Clone 23C6
Applications Flow Cytometry
Applications Immunohistochemistry (Frozen)
Format Purified
Primary or Secondary Primary
Storage Requirements Store at 2-8°C.
Monoclonal or Polyclonal Monoclonal
Host Species Mouse
Antigen CD51/CD61 (Integrin alpha v beta 3)
Gene Alias Integrin av b3, vitronectin Receptor
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Concentration 0.5mg/mL
Species Reactivity Human
Conjugate Unlabeled

The 23C6 monoclonal antibody reacts with the human CD51/CD61 dimer, also known as the integrin αv/β3. CD51, an ∽120kDa surface molecule can also non-covalently associate with other β subunits of the integrin family including β1 (CD29), β5 and β6 to form receptors for extracellular matrix components. Heterodimers of CD51/CD61 are expressed by melanoma cells, endothelial cells and osteoclasts and at very low levels by platelets. The CD51/CD61 complex mediates adhesion to fibrinogen, fibronectin, vitronectin and thrombospondin.