CD51/CD61 (Integrin alpha v beta 3) Mouse anti-Human, Biotin, Clone: 23C6, eBioscience™

Mouse Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 13-0519-80

25UG ANTI-HUMAN CD51/CD61 BIOTIN

UNSPSC: 12352200

Code: Z2

Additional Details:
Additional Details: Weight: 0.25000kg



Disclaimers: For Research Use Only.

Product Code. 15239599

Quantity Price
1 £ 76.0 / 25µg
Estimated Shipment date
from Supplier 08-12-2016
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Description and Specification

Specification

Antigen CD51/CD61 (Integrin alpha v beta 3)
Applications Flow Cytometry
Clone 23C6
Concentration 0.5mg/mL
Conjugate Biotin
Format Conjugated
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Gene Alias Integrin av b3, vitronectin Receptor
Host Species Mouse
Isotype IgG1
Quantity 25μg
Regulatory Status RUO
Species Reactivity Human
Storage Requirements Store at 2-8°C. Do not freeze.
Primary or Secondary Primary
Monoclonal or Polyclonal Monoclonal

The 23C6 monoclonal antibody reacts with the human CD51/CD61 dimer, also known as the integrin αv/β3. CD51, an ∽120kDa surface molecule can also non-covalently associate with other β subunits of the integrin family including β1 (CD29), β5 and β6 to form receptors for extracellular matrix components. Heterodimers of CD51/CD61 are expressed by melanoma cells, endothelial cells and osteoclasts and at very low levels by platelets. The CD51/CD61 complex mediates adhesion to fibrinogen, fibronectin, vitronectin and thrombospondin.