CD49f (Integrin alpha 6) Rat anti-Human, Mouse, eFluor 450, Clone: eBioGoH3 (GoH3), eBioscience™

Rat Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 48-0495-80

UNSPSC: 12352200

Code: Z2

Additional Details:
Additional Details: Weight: 0.25000kg



Disclaimers: For Research Use Only.

Product Code. 15331730

Quantity Price
1 £ 55.0 / 25µg
Estimated Shipment date
from Supplier 10-05-2017
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Description and Specification

Specification

Regulatory Status RUO
Conjugate eFluor 450
Host Species Rat
Quantity 25μg
Primary or Secondary Primary
Applications Flow Cytometry
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material.
Format Conjugated
Gene Alias Integrin a6, ITGA6, VLA6
Monoclonal or Polyclonal Monoclonal
Isotype IgG2a
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Species Reactivity Human, Mouse
Antigen CD49f (Integrin alpha 6)
Concentration 0.2mg/mL
Clone eBioGoH3 (GoH3)

The eBioGoH3 monoclonal antibody reacts with mouse and human CD49f, also known as integrin alpha 6, very late activation antigen 6 (VLA-6 alpha chain), and platelet gpIc. CD49f is a 120 kD transmembrane protein. CD49f associates with CD29, the integrin beta 1 chain, to form the VLA-6 complex; CD49f also associates with CD104, the integrin beta 4 chain, to form the alpha 6 beta 4 complex. CD49f is expressed primarily on T cells, monocytes, platelets, epithelial and endothelial cells. CD49f expression has also been found on germinal center B cells. The eBioGoH3 antibody is cross-reactive to integrin alpha 6 on human, mouse and bovine cells. This antibody has also been reported to have functional activity in blocking the binding of integrin alpha 6 to laminin.