CD49f (Integrin alpha 6) Rat anti-Human, Mouse, eFluor 450, Clone: eBioGoH3 (GoH3), eBioscience™

Rat Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 48-0495-82

UNSPSC: 12352200

Code: Z2

Additional Details:
Additional Details: Weight: 0.25000kg



Disclaimers: For Research Use Only.

Product Code. 15341730

Quantity Price
1 £ 130.12 / 100µg
EU Stock 4
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Description and Specification

Specification

Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material.
Monoclonal or Polyclonal Monoclonal
Primary or Secondary Primary
Host Species Rat
Antigen CD49f (Integrin alpha 6)
Species Reactivity Human, Mouse
Gene Alias Integrin a6, ITGA6, VLA6
Clone eBioGoH3 (GoH3)
Format Conjugated
Isotype IgG2a
Quantity 100μg
Conjugate eFluor 450
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Concentration 0.2mg/mL
Applications Flow Cytometry
Regulatory Status RUO

The eBioGoH3 monoclonal antibody reacts with mouse and human CD49f, also known as integrin alpha 6, very late activation antigen 6 (VLA-6 alpha chain), and platelet gpIc. CD49f is a 120 kD transmembrane protein. CD49f associates with CD29, the integrin beta 1 chain, to form the VLA-6 complex; CD49f also associates with CD104, the integrin beta 4 chain, to form the alpha 6 beta 4 complex. CD49f is expressed primarily on T cells, monocytes, platelets, epithelial and endothelial cells. CD49f expression has also been found on germinal center B cells. The eBioGoH3 antibody is cross-reactive to integrin alpha 6 on human, mouse and bovine cells. This antibody has also been reported to have functional activity in blocking the binding of integrin alpha 6 to laminin.