CD49f (Integrin alpha 6) Rat anti-Human, Mouse, Clone: eBioGoH3 (GoH3), eBioscience™

Rat Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 14-0495-81

UNSPSC: 12352200

Code: Z2

Additional Details:
Additional Details: Weight: 0.01000kg



Disclaimers: For Research Use Only.

Product Code. 15227007

Quantity Price
1 £ 48.31 / 50µg
Estimated Shipment date
from Supplier 08-05-2017
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Description and Specification

Specification

Concentration 0.5mg/mL
Conjugate Unlabeled
Quantity 50μg
Host Species Rat
Monoclonal or Polyclonal Monoclonal
Species Reactivity Human, Mouse
Gene Alias Integrin a6, ITGA6, VLA6
Antigen CD49f (Integrin alpha 6)
Applications Flow Cytometry
Applications Immunohistochemistry (Frozen)
Applications Immunoprecipitation
Storage Requirements Store at 2-8°C.
Clone eBioGoH3 (GoH3)
Isotype IgG2a
Format Purified
Primary or Secondary Primary
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Regulatory Status RUO

The eBioGoH3 monoclonal antibody reacts with mouse and human CD49f, also known as integrin alpha 6, very late activation antigen 6 (VLA-6 alpha chain), and platelet gpIc. CD49f is a 120 kD transmembrane protein. CD49f associates with CD29, the integrin beta 1 chain, to form the VLA-6 complex; CD49f also associates with CD104, the integrin beta 4 chain, to form the alpha 6 beta 4 complex. CD49f is expressed primarily on T cells, monocytes, platelets, epithelial and endothelial cells. CD49f expression has also been found on germinal center B cells. The eBioGoH3 antibody is cross-reactive to integrin alpha 6 on human, mouse and bovine cells. This antibody has also been reported to have functional activity in blocking the binding of integrin alpha 6 to laminin.