CD49f (Integrin alpha 6) Rat anti-Human, Mouse, Biotin, Clone: eBioGoH3 (GoH3), eBioscience™

Rat Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 13-0495-82

UNSPSC: 12352200

Code: Z2

Additional Details:
Additional Details: Weight: 0.25000kg



Disclaimers: For Research Use Only.

Product Code. 15269589

Quantity Price
1 £ 129.54 / 100µg
EU Stock 1
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Description and Specification

Specification

Antigen CD49f (Integrin alpha 6)
Regulatory Status RUO
Concentration 0.5mg/mL
Format Conjugated
Gene Alias Integrin a6, ITGA6, VLA6
Quantity 100μg
Applications Flow Cytometry
Applications Immunohistochemistry (Frozen)
Primary or Secondary Primary
Storage Requirements Store at 2-8°C. Do not freeze.
Host Species Rat
Isotype IgG2a
Species Reactivity Human, Mouse
Clone eBioGoH3 (GoH3)
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Monoclonal or Polyclonal Monoclonal
Conjugate Biotin

The eBioGoH3 monoclonal antibody reacts with mouse and human CD49f, also known as integrin alpha 6, very late activation antigen 6 (VLA-6 alpha chain), and platelet gpIc. CD49f is a 120 kD transmembrane protein. CD49f associates with CD29, the integrin beta 1 chain, to form the VLA-6 complex; CD49f also associates with CD104, the integrin beta 4 chain, to form the alpha 6 beta 4 complex. CD49f is expressed primarily on T cells, monocytes, platelets, epithelial and endothelial cells. CD49f expression has also been found on germinal center B cells. The eBioGoH3 antibody is cross-reactive to integrin alpha 6 on human, mouse and bovine cells. This antibody has also been reported to have functional activity in blocking the binding of integrin alpha 6 to laminin.