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CD49d (Integrin alpha 4) Mouse anti-Rat, APC, Clone: MRa4-1, eBioscience™

Mouse Monoclonal Antibody

Brand:  Affymetrix eBioscience 17-1490-80

Code : NEW

Additional Details : Weight : 0.09500kg

 View more versions of this product

Product Code. 15548016

This item has been discontinued and is no longer available. View the product for possible alternatives or contact our Product Support team on 01509 555888 for assistance

Disclaimers:

For Research Use Only.


Description

Description

The MRa4-1 monoclonal antibody reacts with CD49d, which is also known as the integrin alpha 4 subunit. This 150kDa cell surface protein is expressed by thymocytes, peripheral lymphocytes, monocytes, and eosinophils in complex with either integrin beta1 or integrin beta7. Outside of the immune system, CD49d is also expressed on mast cells, neural crest cells, retinal cells, and dorsal root ganglion neurons. Integrins are responsible for lymphocyte homing to Peyer’s patches and mesenteric lymph nodes, as well as neural development and regeneration. Several ligands have been reported for the integrin a4b1 complex, including VCAM-1 (CD106) and fibronectin.

The MRa1-4 antibody has been reported to inhibit fibronectin binding and lymphocyte migration.
Specifications

Specifications

CD49d (Integrin alpha 4)
MRa4-1
Allophycocyanin
Conjugated
Murine
25μg
Store at 2-8°C. Do not freeze. Light-sensitive material.
Monoclonal
Flow Cytometry
0.2mg/mL
aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
ITGA4
IgG2a
RUO
Primary
Rat