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CD49c (Integrin alpha 3) Mouse anti-Human, APC, Clone: P1B5, eBioscience™

Mouse Monoclonal Antibody

Brand:  Affymetrix eBioscience 17-0494-41

Code : NEW

Additional Details : Weight : 0.23750kg

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Product Code. 15507946

  • £78.88 / 25 tests


Estimated Shipment date
from Supplier 02-10-2017
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Disclaimers:

For Research Use Only.


Description

Description

This P1B5 monoclonal antibody reacts with human CD49c (also known as Integrin alpha 3). Integrins constitute a family of cell surface receptors that mediate adhesion between cells or between a cell and the extracellular matrix. These proteins are heterodimers consisting of two distinct subunits, α and β. Integrins are expressed on hematopoietic, non-hematopoietic, and cancer cells. Integrin-mediated adhesion is regulated by changes in ligand affinity (or activation), cell shape, and integrin clustering and diffusion. Integrin alpha 3 forms a complex with the common beta 1 subunit to form the α3β1 integrin. Studies have demonstrated the involvement of this integrin in wound healing and epithelial migration.

The P1B5 monoclonal antibody has been reported to affect adhesion to type I and VI collagens, as well as fibronectin and laminin.
Specifications

Specifications

CD49c (Integrin alpha 3)
P1B5
APC
Conjugated
Murine
25 Tests
Store at 2-8°C. Do not freeze. Light-sensitive material.
Monoclonal
Flow Cytometry
5μL (0.125μg)/test
aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
VLA3, ITGA3
IgG1
RUO
Primary
Human