CD49a (Integrin alpha 1) Mouse anti-Human, PerCP-eFluor 710, Clone: TS2/7, eBioscience™

Mouse Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 46-9490-41

Code: NEW

Additional Details:
Additional Details: Weight: 0.23750kg



Disclaimers: For Research Use Only.

Product Code. 15519426

Quantity Price
1 £ 68.97 / 25 tests
Estimated Shipment date
from Supplier 02-05-2017
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Description and Specification

Specification

Monoclonal or Polyclonal Monoclonal
Regulatory Status RUO
Isotype IgG1
Host Species Mouse
Species Reactivity Human
Primary or Secondary Primary
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Gene Alias ITGA1, VLA1
Concentration 5μL (0.125μg)/test
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material. This tandem dye is sensitive to photo-induced oxidation. Protect this vial from light during storage
Conjugate PerCP-eFluor 710
Format Conjugated
Antigen CD49a (Integrin alpha 1)
Applications Flow Cytometry
Clone TS2/7
Quantity 25 tests

The monoclonal antibody TS2/7 reacts with human CD49a, also known as integrin alpha 1. CD49a is always associated with CD29 (integrin beta 1) to form a type I transmembrane protein called very late antigen-1 (VLA1). This heterodimer is expressed by endothelial cells, activated T cells, monocytes, a subset of NK cells, a subset of memory T cells, smooth muscle cells, and mesenchymal stem cells. CD49a binds to collagen IV strongly, but also binds to collagen I, laminin, and semaphorin7A. CD49a is involved in cell survival, proliferation, homing, and inflammatory responses.