CD49a (Integrin alpha 1) Mouse anti-Human, PerCP-eFluor 710, Clone: TS2/7, eBioscience™

Mouse Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 46-9490-42

Code: NEW

Additional Details:
Additional Details: Weight: 0.23750kg



Disclaimers: For Research Use Only.

Product Code. 15529426

Quantity Price
1 £ 163.89 / 100 tests
Estimated Shipment date
from Supplier 03-05-2017
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Description and Specification

Specification

Primary or Secondary Primary
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material. This tandem dye is sensitive to photo-induced oxidation. Protect this vial from light during storage
Clone TS2/7
Concentration 5μL (0.125μg)/test
Gene Alias ITGA1, VLA1
Regulatory Status RUO
Antigen CD49a (Integrin alpha 1)
Format Conjugated
Host Species Mouse
Conjugate PerCP-eFluor 710
Isotype IgG1
Applications Flow Cytometry
Quantity 100 tests
Monoclonal or Polyclonal Monoclonal
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Species Reactivity Human

The monoclonal antibody TS2/7 reacts with human CD49a, also known as integrin alpha 1. CD49a is always associated with CD29 (integrin beta 1) to form a type I transmembrane protein called very late antigen-1 (VLA1). This heterodimer is expressed by endothelial cells, activated T cells, monocytes, a subset of NK cells, a subset of memory T cells, smooth muscle cells, and mesenchymal stem cells. CD49a binds to collagen IV strongly, but also binds to collagen I, laminin, and semaphorin7A. CD49a is involved in cell survival, proliferation, homing, and inflammatory responses.