CD47 Rat anti-Mouse, Clone: miap301, Functional Grade, eBioscience™

Rat Monoclonal Antibody, Functional Grade

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 16-0471-85

UNSPSC: 12352200

Code: Z2

Additional Details:
Additional Details: Weight: 0.01000kg



Disclaimers: For Research Use Only.

Product Code. 15278457

Quantity Price
1 £ 219.5 / 500µg
Estimated Shipment date
from Supplier 02-05-2017
Add to basket


Description and Specification

Specification

Concentration 1mg/mL
Applications Flow Cytometry
Applications Functional Assay
Host Species Rat
Quantity 500μg
Primary or Secondary Primary
Format Purified
Regulatory Status RUO
Isotype IgG2a
Antigen CD47
Conjugate Unlabeled
Storage Requirements Store at 2-8°C.
Monoclonal or Polyclonal Monoclonal
Species Reactivity Mouse
Formulation aqueous buffer, no sodium azide
Gene Alias Integrin associated protein, IAP
Clone miap301

The monoclonal antibody miap301 reacts to CD47 also known as integrin-associated protein (IAP), and neurophilin. CD47 is a glycosylated five transmembrane protein with a small cytoplasmic domain. CD47 is involved in adhesion through interactions with SIRP (signal regulator protein) and is non-covalently associated with ß3 integrins CD51/CD61, CD41/CD61. It is also known to be the receptor for thrombospondin. T cell expression of CD47 can mediate activation or apoptosis (in the presence of high levels of thrombospondin). Expression is found in the majority of hematopoietic cells including T and B cells, monocytes, platelets and erythrocytes (as part of the Rh complex). Expression is also found in non-hematopoietic cells.

No crossreactivity is seen against human CD47.