CD47 Rat anti-Mouse, Clone: miap301, Functional Grade, eBioscience™

Rat Monoclonal Antibody, Functional Grade

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 16-0471-81

UNSPSC: 12352200

Code: Z2

Additional Details:
Additional Details: Weight: 0.01000kg



Disclaimers: For Research Use Only.

Product Code. 15268457

Quantity Price
1 £ 60.53 / 50µg
Estimated Shipment date
from Supplier 08-05-2017
Add to basket


Description and Specification

Specification

Formulation aqueous buffer, no sodium azide
Species Reactivity Mouse
Storage Requirements Store at 2-8°C.
Host Species Rat
Isotype IgG2a
Primary or Secondary Primary
Antigen CD47
Applications Flow Cytometry
Applications Functional Assay
Gene Alias Integrin associated protein, IAP
Monoclonal or Polyclonal Monoclonal
Conjugate Unlabeled
Quantity 50μg
Regulatory Status RUO
Concentration 1mg/mL
Clone miap301
Format Purified

The monoclonal antibody miap301 reacts to CD47 also known as integrin-associated protein (IAP), and neurophilin. CD47 is a glycosylated five transmembrane protein with a small cytoplasmic domain. CD47 is involved in adhesion through interactions with SIRP (signal regulator protein) and is non-covalently associated with ß3 integrins CD51/CD61, CD41/CD61. It is also known to be the receptor for thrombospondin. T cell expression of CD47 can mediate activation or apoptosis (in the presence of high levels of thrombospondin). Expression is found in the majority of hematopoietic cells including T and B cells, monocytes, platelets and erythrocytes (as part of the Rh complex). Expression is also found in non-hematopoietic cells.

No crossreactivity is seen against human CD47.