CD47 Rat anti-Mouse, Clone: miap301, eBioscience™

Rat Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 14-0471-82

UNSPSC: 12352200

Code: Z2

Additional Details:
Additional Details: Weight: 0.01000kg



Disclaimers: For Research Use Only.

Product Code. 15236987

Quantity Price
1 £ 66.65 / 100µg
Estimated Shipment date
from Supplier 03-04-2017
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Description and Specification

Specification

Regulatory Status RUO
Applications Flow Cytometry
Applications Immunohistochemistry (Frozen)
Applications Immunoprecipitation
Applications Western Blotting
Host Species Rat
Format Purified
Antigen CD47
Isotype IgG2a
Primary or Secondary Primary
Clone miap301
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Conjugate Unlabeled
Monoclonal or Polyclonal Monoclonal
Storage Requirements Store at 2-8°C.
Concentration 0.5mg/mL
Gene Alias Integrin associated protein, IAP
Quantity 100μg
Species Reactivity Mouse

The monoclonal antibody miap301 reacts to CD47 also known as integrin-associated protein (IAP), and neurophilin. CD47 is a glycosylated five transmembrane protein with a small cytoplasmic domain. CD47 is involved in adhesion through interactions with SIRP (signal regulator protein) and is non-covalently associated with ß3 integrins CD51/CD61, CD41/CD61. It is also known to be the receptor for thrombospondin. T cell expression of CD47 can mediate activation or apoptosis (in the presence of high levels of thrombospondin). Expression is found in the majority of hematopoietic cells including T and B cells, monocytes, platelets and erythrocytes (as part of the Rh complex). Expression is also found in non-hematopoietic cells.

No crossreactivity is seen against human CD47.