CD47 Rat anti-Mouse, APC, Clone: miap301, eBioscience™

Rat Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 17-0471-80

UNSPSC: 12352200

Code: Z2

Additional Details:
Additional Details: Weight: 0.25000kg



Disclaimers: For Research Use Only.

Product Code. 15320630

Quantity Price
1 £ 72.77 / 25µg
Estimated Shipment date
from Supplier 03-04-2017
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Description and Specification

Specification

Concentration 0.2mg/mL
Applications Flow Cytometry
Format Conjugated
Isotype IgG2a
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Conjugate APC
Antigen CD47
Species Reactivity Mouse
Primary or Secondary Primary
Quantity 25μg
Gene Alias Integrin associated protein, IAP
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material.
Clone miap301
Monoclonal or Polyclonal Monoclonal
Regulatory Status RUO
Host Species Rat

The monoclonal antibody miap301 reacts to CD47 also known as integrin-associated protein (IAP), and neurophilin. CD47 is a glycosylated five transmembrane protein with a small cytoplasmic domain. CD47 is involved in adhesion through interactions with SIRP (signal regulator protein) and is non-covalently associated with ß3 integrins CD51/CD61, CD41/CD61. It is also known to be the receptor for thrombospondin. T cell expression of CD47 can mediate activation or apoptosis (in the presence of high levels of thrombospondin). Expression is found in the majority of hematopoietic cells including T and B cells, monocytes, platelets and erythrocytes (as part of the Rh complex). Expression is also found in non-hematopoietic cells.

No crossreactivity is seen against human CD47.