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CD47 Mouse anti-Human, FITC, Clone: 2D3, eBioscience™

Mouse Monoclonal Antibody

Brand:  Affymetrix eBioscience 11-0478-41

Code : NEW

Additional Details : Weight : 0.23750kg

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Product Code. 15586406

  • £55.00 / 25 tests


EU Stock 3
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Disclaimers:

For Research Use Only.


Specifications

Description

The monoclonal antibody 2D3 reacts to CD47 also known as integrin-associated protein (IAP), and neurophilin. CD47 is a glycosylated five transmembrane protein with a small alternatively spliced cytoplasmic domain. CD47 is involved in adhesion through interactions with SIRP (signal regulator protein) and is non-covalently associated with β3 integrins CD51/CD61 and CD41/CD61. Furthermore this interaction can mediate bi-directional signaling to modify neural synaptic activity and regulate the phagocytic activities of macrophages. CD47 is the receptor for thrombospondin. T cell expression of CD47 can mediate activation or apoptosis (in the presence of high levels of thrombospondin). Expression is found in the majority of hematopoietic cells including T and B cells, monocytes, platelets and erythrocytes (as part of the Rh complex). Expression is also found in non-hematopoietic cells.
Description & Specifications

Specifications

CD47
2D3
FITC
aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Murine
25 Tests
Store at 2-8°C. Do not freeze. Light-sensitive material.
Monoclonal
Flow Cytometry
5μL (1μg)/test
Conjugated
Integrin associated protein, IAP
IgG1
RUO
Primary
Human