CD45R (B220) Rat anti-Canine, PE, Clone: YKIX753.22, eBioscience™

Rat Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 12-5451-41

Code: NEW

Additional Details:
Additional Details: Weight: 0.23750kg



Disclaimers: For Research Use Only.

Product Code. 15557006

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Description and Specification

Specification

Antigen CD45R (B220)
Applications Flow Cytometry
Clone YKIX753.22
Concentration 5μL (0.0075μg)/test
Conjugate PE
Format Conjugated
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Host Species Rat
Isotype IgG2b
Quantity 25 Tests
Regulatory Status RUO
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material.
Primary or Secondary Primary
Monoclonal or Polyclonal Monoclonal
Target Species Canine

The YKIX753.22 monoclonal antibody reacts with canine CD45R. In dogs, CD45R is expressed on B cells and peripheral T cells. In addition, CD45 exists as multiple isoforms due to alternative splicing. Some isoforms of CD45 are CD45RA, CD45RB, or CD45RO depending on the exon used during transcription. The C-terminal domain of CD45 exhibits tyrosine phosphatase activity that enables signaling from by T cell and B cell receptors following activation.

This antibody has been reported to promote cell depletion via antibody-dependent cell-mediated cytotoxicity when used in conjunction with YKIX716.13.