CD45R (B220) Rat anti-Canine, PE, Clone: YKIX753.22, eBioscience™

Rat Monoclonal Antibody

Brand: Affymetrix eBioscience

Manufacturer Part Number: 12-5451-41

Code: NEW

Additional Details:
Additional Details: Weight: 0.23750kg

Disclaimers: For Research Use Only.

Product Code. 15557006


This item has been discontinued and is no longer available. View the product for possible alternatives or contact our Product Support team on 01509 555888 for assistance

Description and Specification


Antigen CD45R (B220)
Applications Flow Cytometry
Clone YKIX753.22
Concentration 5μL (0.0075μg)/test
Conjugate PE
Format Conjugated
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Host Species Rat
Isotype IgG2b
Quantity 25 Tests
Regulatory Status RUO
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material.
Primary or Secondary Primary
Monoclonal or Polyclonal Monoclonal
Target Species Canine

The YKIX753.22 monoclonal antibody reacts with canine CD45R. In dogs, CD45R is expressed on B cells and peripheral T cells. In addition, CD45 exists as multiple isoforms due to alternative splicing. Some isoforms of CD45 are CD45RA, CD45RB, or CD45RO depending on the exon used during transcription. The C-terminal domain of CD45 exhibits tyrosine phosphatase activity that enables signaling from by T cell and B cell receptors following activation.

This antibody has been reported to promote cell depletion via antibody-dependent cell-mediated cytotoxicity when used in conjunction with YKIX716.13.