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CD41a, clone: HIP8, eBioscience™

Mouse Monoclonal Antibody

Brand:  Affymetrix eBioscience 14-0419-80

Code : Z2

Additional Details : Weight : 0.01000kg

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Product Code. 15246947

  • £31.01 / 25µg


Estimated Shipment
01-03-2018
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Disclaimers:

For Research Use Only.


Description

Description

Description: The HIP8 monoclonal antibody reacts with the human CD41 molecule, the integrin alphaIIb also known as platelet GPIIb. CD41 non-covalently associates with integrin beta3 (GPIIIa, CD61) and is expressed by megakaryocytes and platelets. The CD41/CD61 complex is a receptor for fibronectin, fibrinogen, von Willebrand factor, vitronectin and thrombospondin and mediates platelets aggregation. HIP8 blocks platelet aggregation.Applications Reported: The HIP8 antibody has been reported for use in flow cytometric analysis, and immunohistochemical staining.Applications Tested: The HIP8 antibody has been tested by flow cytometric analysis of human platelets. This can be used at less than or equal to 0.5 μg per test. A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest.Purity: Greater than 90%, as determined by SDS-PAGE.Aggregation: Less than 10%, as determined by HPLC.Filtration: 0.2μm post-manufacturing filtered.
Specifications

Specifications

CD41a
HIP8
Unconjugated
Purified
IgG1
RUO
Primary
Human
Immunohistochemistry
0.5mg/mL
aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Murine
25μg
Store at 2-8°C.
Monoclonal
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