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CD41a, clone: HIP8, eBioscience™

Mouse Monoclonal Antibody

Brand:  Affymetrix eBioscience 14-0419-80

Code : Z2

Additional Details : Weight : 0.01000kg

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Product Code. 15246947

  • £31.01 / 25Āµg


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Description

Description

Description: The HIP8 monoclonal antibody reacts with the human CD41 molecule, the integrin alphaIIb also known as platelet GPIIb. CD41 non-covalently associates with integrin beta3 (GPIIIa, CD61) and is expressed by megakaryocytes and platelets. The CD41/CD61 complex is a receptor for fibronectin, fibrinogen, von Willebrand factor, vitronectin and thrombospondin and mediates platelets aggregation. HIP8 blocks platelet aggregation.Applications Reported: The HIP8 antibody has been reported for use in flow cytometric analysis, and immunohistochemical staining.Applications Tested: The HIP8 antibody has been tested by flow cytometric analysis of human platelets. This can be used at less than or equal to 0.5 μg per test. A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest.Purity: Greater than 90%, as determined by SDS-PAGE.Aggregation: Less than 10%, as determined by HPLC.Filtration: 0.2μm post-manufacturing filtered.
Specifications

Specifications

CD41a
Monoclonal
0.5mg/mL
PBS with 0.09% sodium azide; pH 7.2
P08514
BDPLT2, CD41, CD41B, GP2B, GPIIb, GT, GTA, HPA3, GPalpha IIb, integrin alpha-IIb, platelet fibrinogen receptor, alpha subunit, platelet membrane glycoprotein IIb, platelet-specific antigen BAK, ITGA2B
Murine
Affinity chromatography
RUO
Antibody
Monoclonal
Human
Flow CytometryĆ¾Immunohistochemistry
HIP8
Unconjugated
ITGA2B
Purified
ITGA2B
IgG1, kappa
25μg
Store at 2-8°C.
Primary
3674
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