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CD40 Monoclonal Antibody (5C3), PerCP-eFluor™ 710, eBioscience™, Invitrogen™

Mouse Monoclonal Antibody

£274.00

Specifications

Antigen CD40
Clone 5C3
Concentration 5 μL/Test
Applications Flow Cytometry
Classification Monoclonal
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Products 1
Product Code Brand Quantity Price Quantity & Availability  
Product Code Brand Quantity Price Quantity & Availability  
15589116
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Affymetrix eBioscience
46-0409-42
100 Tests
£274.00
100 tests
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Description

Description

Description: The 5C3 monoclonal antibody reacts with human CD40, a 45-50 kDa type I transmembrane glycoprotein. CD40 is a member of the TNFR family and is expressed by B lymphocytes, follicular dendritic cells, thymic epithelium, and a subset of peripheral T cells. CD40 regulates B cell development and maturation by inducing Ig isotype-switching and in combination with other signals such as IL-4, protects B cells from surface Ig-induced apoptosis and promotes proliferation. Interaction of CD40 with CD154 (gp39), its ligand on T cells, is important in T-B cell crosstalk and plays a role in costimulation and immune regulation. 5C3 is reported to be used for activation of B cells in in vitro functional assays. Applications Reported: This 5C3 antibody has been reported for use in flow cytometric analysis. Applications Tested: This 5C3 antibody has been pre-titrated and tested by flow cytometric analysis of normal human peripheral blood cells. This can be used at 5 μL (0.03 μg) per test. A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. PerCP-eFluor™ 710 emits at 710 nm and is excited with the blue laser (488 nm); it can be used in place of PerCP-Cyanine5.5. We recommend using a 710/50 bandpass filter, however, the 695/40 bandpass filter is an acceptable alternative.

CD40 Monoclonal antibody specifically detects CD40 in Human samples. It is validated for Flow Cytometry.
Specifications

Specifications

CD40
5 μL/Test
Monoclonal
Liquid
RUO
P25942
CD40
Primary
4° C, store in dark, DO NOT FREEZE!
CD40
5C3
Flow Cytometry
PerCP-eFluor 710
Mouse
Human
958
IgG1 κ
Affinity chromatography
Antibody
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