CD40 Armenian Hamster anti-Mouse, Rat, FITC, Clone: HM40-3, eBioscience™

Armenian Hamster Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 11-0402-86

UNSPSC: 12352200

Code: Z2

Additional Details:
Additional Details: Weight: 0.25000kg



Disclaimers: For Research Use Only.

Product Code. 15228079

Quantity Price
1 £ 298.99 / 1mg
Estimated Shipment date
from Supplier 03-05-2017
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Description and Specification

Specification

Concentration 0.5mg/mL
Species Reactivity Mouse, Rat
Isotype IgM
Quantity 1mg
Conjugate FITC
Format Conjugated
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material.
Antigen CD40
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Applications Flow Cytometry
Monoclonal or Polyclonal Monoclonal
Regulatory Status RUO
Host Species Armenian Hamster
Clone HM40-3
Gene Alias TNFRSF5
Primary or Secondary Primary

The HM40-3 monoclonal antibody reacts with mouse and rat CD40, a 45-50kDa type I transmembrane glycoprotein. CD40 is a member of the TNFR family and is expressed by mouse B lymphocytes, follicular dendritic cells, thymic epithelium, and a subset of peripheral T cells. CD40 regulates B cell development/maturation by inducing Ig isotype switching and in combination with other signals such as IL-4, protects B cells from surface Ig-induced apoptosis and promotes proliferation. Interaction of CD40 with CD154 (gp39), its ligand on T cells, is important in T-B cell crosstalk and plays a role in costimulation and immune regulation.