CD40 Armenian Hamster anti-Mouse, Rat, FITC, Clone: HM40-3, eBioscience™

Armenian Hamster Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 11-0402-85

500UG ANTI-MOUSE/RAT CD40 FITC

UNSPSC: 12352200

Code: Z2

Additional Details:
Additional Details: Weight: 0.25000kg



Disclaimers: For Research Use Only.

Product Code. 15218079

Quantity Price
1 £ 213.0 / 500µg
Estimated Shipment date
from Supplier 27-02-2017
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Description and Specification

Specification

Antigen CD40
Format Conjugated
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Host Species Armenian Hamster
Applications Flow Cytometry
Isotype IgM
Quantity 500μg
Primary or Secondary Primary
Monoclonal or Polyclonal Monoclonal
Conjugate FITC
Gene Alias TNFRSF5
Regulatory Status RUO
Species Reactivity Mouse, Rat
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material.
Clone HM40-3
Concentration 0.5mg/mL

The HM40-3 monoclonal antibody reacts with mouse and rat CD40, a 45-50kDa type I transmembrane glycoprotein. CD40 is a member of the TNFR family and is expressed by mouse B lymphocytes, follicular dendritic cells, thymic epithelium, and a subset of peripheral T cells. CD40 regulates B cell development/maturation by inducing Ig isotype switching and in combination with other signals such as IL-4, protects B cells from surface Ig-induced apoptosis and promotes proliferation. Interaction of CD40 with CD154 (gp39), its ligand on T cells, is important in T-B cell crosstalk and plays a role in costimulation and immune regulation.