CD40 Armenian Hamster anti-Mouse, Rat, FITC, Clone: HM40-3, eBioscience™

Armenian Hamster Monoclonal Antibody

Brand:  Affymetrix eBioscience 11-0402-82

Product Code. 15208079

Disclaimers:

For Research Use Only.

Description

The HM40-3 monoclonal antibody reacts with mouse and rat CD40, a 45-50kDa type I transmembrane glycoprotein. CD40 is a member of the TNFR family and is expressed by mouse B lymphocytes, follicular dendritic cells, thymic epithelium, and a subset of peripheral T cells. CD40 regulates B cell development/maturation by inducing Ig isotype switching and in combination with other signals such as IL-4, protects B cells from surface Ig-induced apoptosis and promotes proliferation. Interaction of CD40 with CD154 (gp39), its ligand on T cells, is important in T-B cell crosstalk and plays a role in costimulation and immune regulation.

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Specifications

• Antigen: CD40
• Clone: HM40-3
• Conjugate: FITC
• Formulation: aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
• Host Species: Armenian Hamster
• Quantity: 100μg
• Storage Requirements: Store at 2-8°C. Do not freeze. Light-sensitive material.
• Monoclonal or Polyclonal: Monoclonal

• Applications: Flow Cytometry
• Concentration: 0.5mg/mL
• Format: Conjugated
• Gene Alias: TNFRSF5
• Isotype: IgM
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Target Species: Rat