CD40 Armenian Hamster anti-Mouse, Rat, eFluor 450, Clone: HM40-3, eBioscience™

Armenian Hamster Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 48-0402-80

Code: NEW

Additional Details:
Additional Details: Weight: 0.09500kg



Disclaimers: For Research Use Only.

Product Code. 15599666

Quantity Price
1 £ 78.88 / 25µg
Estimated Shipment date
from Supplier 03-04-2017
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Description and Specification

Specification

Applications Flow Cytometry
Monoclonal or Polyclonal Monoclonal
Primary or Secondary Primary
Conjugate eFluor 450
Antigen CD40
Host Species Armenian Hamster
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Concentration 0.2mg/mL
Quantity 25μg
Format Conjugated
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material.
Species Reactivity Mouse, Rat
Gene Alias TNFRSF5
Isotype IgM
Clone HM40-3
Regulatory Status RUO

The HM40-3 monoclonal antibody reacts with mouse and rat CD40, a 45-50kDa type I transmembrane glycoprotein. CD40 is a member of the TNFR family and is expressed by mouse B lymphocytes, follicular dendritic cells, thymic epithelium, and a subset of peripheral T cells. CD40 regulates B cell development/maturation by inducing Ig isotype switching and in combination with other signals such as IL-4, protects B cells from surface Ig-induced apoptosis and promotes proliferation. Interaction of CD40 with CD154 (gp39), its ligand on T cells, is important in T-B cell crosstalk and plays a role in costimulation and immune regulation.