CD40 Armenian Hamster anti-Mouse, Rat, Clone: HM40-3, Functional Grade, eBioscience™

Armenian Hamster Monoclonal Antibody, Functional Grade

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 16-0402-82

100UG:ANTI-MOUSE/RAT CD40 FUNCTIONAL GRADE

UNSPSC: 12352200

Code: Z2

Additional Details:
Additional Details: Weight: 0.01000kg



Disclaimers: For Research Use Only.

Product Code. 15208447

Quantity Price
1 £ 103.33 / 100µg
Estimated Shipment date
from Supplier 29-03-2017
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Description and Specification

Specification

Storage Requirements Store at 2-8°C.
Monoclonal or Polyclonal Monoclonal
Conjugate Unlabeled
Antigen CD40
Format Purified
Formulation aqueous buffer, no sodium azide
Gene Alias TNFRSF5
Host Species Armenian Hamster
Applications Flow Cytometry
Applications Functional Assay
Isotype IgM
Quantity 100μg
Regulatory Status RUO
Species Reactivity Mouse, Rat
Primary or Secondary Primary
Clone HM40-3
Concentration 1mg/mL

The HM40-3 monoclonal antibody reacts with mouse and rat CD40, a 45-50kDa type I transmembrane glycoprotein. CD40 is a member of the TNFR family and is expressed by mouse B lymphocytes, follicular dendritic cells, thymic epithelium, and a subset of peripheral T cells. CD40 regulates B cell development/maturation by inducing Ig isotype switching and in combination with other signals such as IL-4, protects B cells from surface Ig-induced apoptosis and promotes proliferation. Interaction of CD40 with CD154 (gp39), its ligand on T cells, is important in T-B cell crosstalk and plays a role in costimulation and immune regulation.