CD40 Armenian Hamster anti-Mouse, Rat, Clone: HM40-3, Functional Grade, eBioscience™

Armenian Hamster Monoclonal Antibody, Functional Grade

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 16-0402-82

UNSPSC: 12352200

Code: Z2

Additional Details:
Additional Details: Weight: 0.01000kg



Disclaimers: For Research Use Only.

Product Code. 15208447

Quantity Price
1 £ 103.33 / 100µg
Estimated Shipment date
from Supplier 04-05-2017
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Description and Specification

Specification

Monoclonal or Polyclonal Monoclonal
Storage Requirements Store at 2-8°C.
Conjugate Unlabeled
Primary or Secondary Primary
Applications Flow Cytometry
Applications Functional Assay
Isotype IgM
Clone HM40-3
Format Purified
Regulatory Status RUO
Antigen CD40
Concentration 1mg/mL
Species Reactivity Mouse, Rat
Quantity 100μg
Gene Alias TNFRSF5
Host Species Armenian Hamster
Formulation aqueous buffer, no sodium azide

The HM40-3 monoclonal antibody reacts with mouse and rat CD40, a 45-50kDa type I transmembrane glycoprotein. CD40 is a member of the TNFR family and is expressed by mouse B lymphocytes, follicular dendritic cells, thymic epithelium, and a subset of peripheral T cells. CD40 regulates B cell development/maturation by inducing Ig isotype switching and in combination with other signals such as IL-4, protects B cells from surface Ig-induced apoptosis and promotes proliferation. Interaction of CD40 with CD154 (gp39), its ligand on T cells, is important in T-B cell crosstalk and plays a role in costimulation and immune regulation.