CD40, Functional Grade, clone: HM40-3, eBioscience™
Armenian Hamster Monoclonal Antibody
Brand: Affymetrix eBioscience 16-0402-82
Code : Z2
Additional Details : Weight : 0.01000kg
DescriptionThe HM40-3 monoclonal antibody reacts with mouse and rat CD40, a 45-50kDa type I transmembrane glycoprotein. CD40 is a member of the TNFR family and is expressed by mouse B lymphocytes, follicular dendritic cells, thymic epithelium, and a subset of peripheral T cells. CD40 regulates B cell development/maturation by inducing Ig isotype switching and in combination with other signals such as IL-4, protects B cells from surface Ig-induced apoptosis and promotes proliferation. Interaction of CD40 with CD154 (gp39), its ligand on T cells, is important in T-B cell crosstalk and plays a role in costimulation and immune regulation.
|Store at 2-8°C.|
|aqueous buffer, no sodium azide|
For Research Use Only.