CD40 Armenian Hamster anti-Mouse, Rat, Clone: HM40-3, Functional Grade, eBioscience™

Armenian Hamster Monoclonal Antibody, Functional Grade

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 16-0402-81

UNSPSC: 12352200

Code: Z2

Additional Details:
Additional Details: Weight: 0.01000kg



Disclaimers: For Research Use Only.

Product Code. 15298437

Quantity Price
1 £ 60.53 / 50µg
Estimated Shipment date
from Supplier 05-05-2017
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Description and Specification

Specification

Primary or Secondary Primary
Gene Alias TNFRSF5
Applications Flow Cytometry
Applications Functional Assay
Host Species Armenian Hamster
Quantity 50μg
Monoclonal or Polyclonal Monoclonal
Regulatory Status RUO
Antigen CD40
Isotype IgM
Formulation aqueous buffer, no sodium azide
Conjugate Unlabeled
Format Purified
Concentration 1mg/mL
Storage Requirements Store at 2-8°C.
Species Reactivity Mouse, Rat
Clone HM40-3

The HM40-3 monoclonal antibody reacts with mouse and rat CD40, a 45-50kDa type I transmembrane glycoprotein. CD40 is a member of the TNFR family and is expressed by mouse B lymphocytes, follicular dendritic cells, thymic epithelium, and a subset of peripheral T cells. CD40 regulates B cell development/maturation by inducing Ig isotype switching and in combination with other signals such as IL-4, protects B cells from surface Ig-induced apoptosis and promotes proliferation. Interaction of CD40 with CD154 (gp39), its ligand on T cells, is important in T-B cell crosstalk and plays a role in costimulation and immune regulation.