CD40 Armenian Hamster anti-Mouse, Rat, Clone: HM40-3, eBioscience™

Armenian Hamster Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 14-0402-81

50UG:ANTI-MOUSE/RAT CD40 PURIFIED 50 UG

UNSPSC: 12352200

Code: Z2

Additional Details:
Additional Details: Weight: 0.01000kg



Disclaimers: For Research Use Only.

Product Code. 15256937

Quantity Price
1 £ 70.0 / 50µg
Estimated Shipment date
from Supplier 24-02-2017
Add to basket


Description and Specification

Specification

Antigen CD40
Format Purified
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Gene Alias TNFRSF5
Host Species Armenian Hamster
Applications Flow Cytometry
Applications Functional Assay
Applications Immunohistochemistry
Isotype IgM
Quantity 50μg
Regulatory Status RUO
Species Reactivity Mouse, Rat
Storage Requirements Store at 2-8°C.
Primary or Secondary Primary
Monoclonal or Polyclonal Monoclonal
Clone HM40-3
Concentration 0.5mg/mL
Conjugate Unlabeled

The HM40-3 monoclonal antibody reacts with mouse and rat CD40, a 45-50kDa type I transmembrane glycoprotein. CD40 is a member of the TNFR family and is expressed by mouse B lymphocytes, follicular dendritic cells, thymic epithelium, and a subset of peripheral T cells. CD40 regulates B cell development/maturation by inducing Ig isotype switching and in combination with other signals such as IL-4, protects B cells from surface Ig-induced apoptosis and promotes proliferation. Interaction of CD40 with CD154 (gp39), its ligand on T cells, is important in T-B cell crosstalk and plays a role in costimulation and immune regulation.