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CD4 Rat anti-Mouse, eFluor® 506, Clone: RM4-5, eBioscience™

Rat Monoclonal Antibody

£70.50 - £142.00

Specifications

Antigen CD4
Clone RM4-5
Target Species Mouse
Conjugate eFluor™ 506
Isotype IgG2a, kappa
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Products 2
Product Code Brand Quantity Price Quantity & Availability  
Product Code Brand Quantity Price Quantity & Availability  
15570637
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Affymetrix eBioscience
69-0042-80
25 μg £70.50
25µg View alternative products
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Estimated Shipment
26-11-2020
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15580637
View Documents
Affymetrix eBioscience
69-0042-82
100 μg £142.00
100µg View alternative products
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Description

Description

The CD4 antigen is involved in the recognition of MHC class II molecules and is a co-receptor for HIV. CD4 is primarily expressed in a subset of T-lymphocytes, also referred to as T helper cells, but may also be expressed by other cells in the immune system, such as monocytes, macrophages, and dendritic cells. At the tissue level, CD4 expression may be detected in thymus, lymph nodes, tonsils, and spleen, and also in specific regions of the brain, gut, and other non-lymphoid tissues. CD4 functions to initiate or augment the early phase of T-cell activation through its association with the T-cell receptor complex and protein tyrosine kinase, Lck. It may also function as an important mediator of direct neuronal damage in infectious and immune-mediated diseases of the central nervous system. Multiple alternatively spliced transcripts have been identified in this gene [RefSeq, July 2017].
Specifications

Specifications

CD4
Mouse
IgG2a, kappa
Monoclonal
Liquid
Antibody
4° C, store in dark, DO NOT FREEZE!
RM4-5
eFluor™ 506
Flow Cytometry
Primary
Monoclonal
PBS with 0.1% gelatin and 0.09% sodium azide; pH 7.2
RUO

For Research Use Only.