CD4 Monoclonal Antibody (4SM95), eFluor™ 570, eBioscience™, Invitrogen™

Rat Monoclonal Antibody

Product Code	Brand	Quantity
15548966	Affymetrix eBioscience 41-9766-80	25 μg
15558966	Affymetrix eBioscience 41-9766-82	100 μg

Description

The CD4 antigen is involved in the recognition of MHC class II molecules and is a co-receptor for HIV. CD4 is primarily expressed in a subset of T-lymphocytes, also referred to as T helper cells, but may also be expressed by other cells in the immune system, such as monocytes, macrophages, and dendritic cells. At the tissue level, CD4 expression may be detected in thymus, lymph nodes, tonsils, and spleen, and also in specific regions of the brain, gut, and other non-lymphoid tissues. CD4 functions to initiate or augment the early phase of T-cell activation through its association with the T-cell receptor complex and protein tyrosine kinase, Lck. It may also function as an important mediator of direct neuronal damage in infectious and immune-mediated diseases of the central nervous system. Multiple alternatively spliced transcripts have been identified in this gene [RefSeq, July 2017].

CD4 Monoclonal antibody specifically detects CD4 in Mouse samples. It is validated for Immunocytochemistry, Immunohistochemistry (Paraffin).

Specifications

• Antigen: CD4
• Classification: Monoclonal
• Form: Liquid
• Regulatory Status: RUO
• Gene Accession No.: P06332
• Isotype: IgG1 κ
• Purification Method: Affinity chromatography

• Clone: 4SM95
• Conjugate: eFluor 570
• Host Species: Rat
• Target Species: Mouse
• Gene ID (Entrez): 12504
• Primary or Secondary: Primary
• Product Type: Antibody

For Research Use Only.