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CD4/CD25 Mouse anti-Human, FITC, PE, eBioscience™

Antibody Cocktail

£103.00 - £237.85

Specifications

Antigen CD4, CD25
Clone RPA-T4 (CD4) and BC96 (CD25)
Target Species Human
Conjugate FITC, PE
Applications Flow Cytometry
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Product Code Brand Quantity Price Quantity & Availability  
15568316
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Affymetrix eBioscience
22-8425-71
25 Tests £103.00
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Estimated Shipment
30-11-2020
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15578316
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Affymetrix eBioscience
22-8425-73
100 Tests This item is currently unavailable or has been discontinued.
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Description

Description

The CD4 antigen is involved in the recognition of the type II MHC antigen. It is also a receptor for HIV. It is present on most T helper cells and normal thymocytes. The cytoplasmic portion of CD4 is associated with p56lck tyrosine kinase. CD4 expression is commonly found in human lymph nodes and tonsils. CD44 is a type 1 transmembrane glycoprotein also known as Phagocytic Glycoprotein-1 (pgp-1) and HCAM. CD44 is the receptor for hyaluronate and exists as a large number of different isoforms due to alternative RNA splicing. The major isoform expressed on lymphocytes, myeloid cells, and erythrocytes is a glycosylated type 1 transmembrane protein. Other isoforms contain glycosaminoglycans and are expressed on hematopoietic and non-hematopoietic cells. CD44 is involved in adhesion of leukocytes to endothelial cells, stromal cells, and the extracellular matrix. CD25: IL2 receptor alpha (IL2RA) and beta (IL2RB) chains, together with the common gamma chain (IL2RG), constitute the high-affinity IL2 receptor. Homodimeric alpha chains (IL2RA) result in low-affinity receptor, while homodimeric beta (IL2RB) chains produce a medium-affinity receptor. Normally an integral-membrane protein, soluble IL2RA has been isolated and determined to result from extracellular proteolyisis. Alternately-spliced IL2RA mRNAs have been isolated, but the significance of each is presently unknown. Mutations in this gene are associated with interleukin 2 receptor alpha deficiency.
Specifications

Specifications

CD4, CD25
Human
Flow Cytometry
Conjugated
Store at 2-8°C. Do not freeze. Light-sensitive material.
RPA-T4 (CD4) and BC96 (CD25)
FITC, PE
Monoclonal
aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
RUO

For Research Use Only.